Environmental Sciences Division
Microbial Genomics Group

Funded Projects Lab Equipment Genomics Staff Functional Genomics Microbial Ecology Publications

Funded Projects

Currently-Funded Projects

  • "HERMES: Hierarchical Experimental Responses at Macromolecular to Ecosystem Scales." Project Website: http://www.esd.ornl.gov/PGG/HERMES/. Christopher Schadt Co-Investigator DOE-PER Program (Lead PI: Steve Defazio) - 2004.
  • "An Integrated Assessment of Geochemical and Community Structure Determinants of Metal Reduction Rates in Subsurface Sediments." Christopher Schadt Co-Investigator DOE-NABIR Program (Lead PI: Tony Palumbo) - 2004.
  • Integrated analysis of protein complexes and regulatory networks involved in anaerobic energy metabolism of Shewanella oneidensis MR-1, PI, with Larimer, Nealson, Thompson, et al. DOE Microbial Cell Project (Oct. 1, 01 – Sept. 30, 04).
  • The dynamics of cellular stress responses in Deinococcus radiodurans, CO-PI, with Mike Daly et al. DOE Microbial Cell Project (Oct. 1, 01 – Sept. 30, 04).
  • The Rhodopseudomonas palustris Microbial Cell Project, CO-PI, with Tabita, Thompson, et al. DOE Microbial Cell Project (Oct. 1, 01 – Sept. 30, 04).
  • Community-Wide Analysis of Unique Sequences and Functions from Uncultured Microorganisms, CO-PI with Fields, ORNL Laboratory Directed Development and Research Program (Oct. 1, 01 – Sept. 30, 04).
  • Gene Expression Profiles in Nitrosomonas europaea, an Obligate Chemolithoautotroph. Co-PI with Arp and Klotz. DOE Microbial Genome Program (Oct. 1, 01 – Sept. 30, 04).
  • Use of DNA Microarrays for Understanding the Genetic and Metabolic Regulation of Carbon Dioxide Fixation and Hydrogen Production in Rhodopseudomonas palustris. Co-PI with Harwood and Thompson. DOE Microbial Genome Program (Oct. 1, 01 – Sept. 30, 04).
  • Linking genomics to cellular responses and mechanisms for radiation resistance in Deinococcus radiodurans, PI with Robert Hettich, Robert Burlage, Alex Beliaev, and Dorothea Thompson, LDRD, Oak Ridge National Laboratory (Oct. 1, 2000 – Set. 30, 2003).
  • Shewanella putrefaciens: Regulation of the genes and proteins involved in metal reduction pathways. DOE NABIR Program (Oct. 1, 1999 to Sept 30, 2002) (CO-PI with Carol Giometti).
  • Understanding the roles of spatial isolation and carbon in microbial community structure dynamics, and activity for bioremediation (Co-PI with Tiedje and Treves). DOE NABIR program (Oct. 1, 2000 to Sept. 30, 2003).
  • Development and use of 16S rRNA gene-based oligonucleotide microarrays for Assessing Microbial Community Composition and Dynamics. (PI with Thompson, Hurt, Xu, and Xu) DOE NABIR program (Oct. 1, 2000 to Sept. 30, 2003).
  • Field-scale evaluation of biostimulation for remediation of uranium–contaminated groundwater at a proposed NABIR Field research center in Oak Ridge TN (Co-PI with Criddle, Jardine, Palumbo, Kitanidis, Hopkins). DOE NABIR program (Oct. 1, 2000 to Sept. 30, 2003).
  • Center for research on enhancing carbon sequestration in terrestrial ecosystems (Co-PI with Gary Jacobs et al.) (Oct. 1, 99 to Sept. 30, 2002)
  • Coupling process and microbial community studies to understand the mechanisms controlling carbon preservation and nitrogen loss in marine sediments. (Co-PI with Tiedje, Devol, Massol-Deya, and Palumbo) DOE Biotechnological Investigations --- Ocean Margin Program (Oct. 1, 2000 – Set. 30, 2003).
  • Microbially mediated immobilization of contaminants through in situ biostimulation: Scale up of EMSP project 55267 (Co-PI with Jardine, Brooks) DOE EM Science Program (Oct. 1, 2000 to Sept. 30, 2003).
  • Computational structure characterization of metal-reduction proteins in microbe. (Co-PI with Ying Xu, Dong Xu, et al.) DOE Experimental and Computational Structural Biology (Oct. 1, 2000 – Set. 30, 2003).
  • Enhancing carbon sequestration and reclamation of degraded lands with fossil fuel combustion byproducts. (Co-PI with Palumbo et al.) DOE Fossil Energy Program (Oct. 1, 2000 – Set. 30, 2003).

Accomplished Projects

  • Development of microchip-based detection methods: a high throughput microbial detection tool for bioremediation and carbon sequestration. Seed Money Program, Oak Ridge National Lab (Feb. 1, 2000 to Set. 30, 2001). (PI)
  • Exploring whole genome sequence information for defining the functions of unknown genes and regulatory networks in dissimilatory metal reduction pathways (PI with Nealson and Tiedje) DOE Microbial Genome Program (Oct. 1, 1998 to Sept. 30, 2001).
  • Noncompetitive diversity patterns in soils: their causes and implications (Co-PI with Tiedje, O’Neill, and Palumbo). DOE NABIR program (Oct. 1, 97 to Sept. 30, 2000)
  • Linking process and population studies to understand the nitrogen loss mechanisms of Pacific Northwest marine sediments (Co-PI with Tiedje, Devol, Massol-Deya, and Palumbo). DOE Biotechnological Investigations - Ocean Margin Program (Oct. 1, 97 - Sept 30, 2000).
  • Rapid gene probe for microorganisms monitoring by novel MS approaches (Co-PI with W. Chen). DOE NABIR program (Oct. 1, 99 to Sept. 30, 2002).
  • Isolation of Proteins Involved in Metal Reduction from Shewanella oneidensis MR-1 with Mass Spectrometry, LDRD Program, Oak Ridge National Lab (March 1, 2000 to Sept 30, 2000)
  • Development and testing of molecular probes that distinguish effective TCE-cooxidizers from ineffective TCE-cooxidizers: a potential tool for site assessment and management (Co-PI with Tiedje). Department of Defense (Sept. 1, 1996 to Sept. 1, 1998).
  • Enzymes from extremophiles in bioremediation and bioprocessing (Co-PI, with Woodward, Palumbo et al.), Oak Ridge National Laboratory (Sept. 1, 96 to Aug. 31, 98).
  • Development of gene probes for nitrate reductase in environmental media: a tool to evaluate nitrogen retention in watersheds (Co-PI with Mulholland, Garten), Oak Ridge National Laboratory (Jan. 1, 98 to Dec. 30, 98).

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Last Modified: September 7, 2005