The Health Sciences Research Division (HSRD) of Oak Ridge National Laboratory conducts a broad range of basic and applied research in the general area of life sciences. Cause-effect mechanisms of action are studied at several levels of biological structure that include subatomic, atomic, molecular, cellular, tissue, organ, and organism toxicological perspectives.
HSRD has developed an almost unique capacity for analytical study that includes source evaluation, environment transport, field characterization, biomonitoring, and dose-response analysis. The integrated processes span from the conceptual interface--biological and chemical processes merge into physical interactions--to various toxicological endpoints in cells, laboratory animals, and humans.
In addition, basic radiological, chemical, and biological processes are used to predict potential risks to humans from exposures to hazardous agents for which (1) no directly relevant databases are available, (2) available data are ambiguous as demonstrated by electric/magnetic fields and low concentrations of established hazardous chemicals, or (3) exposures may illicit an untoward response only when combined with joint exposures to other insults.
Research areas include basic, applied, and project-specific studies for the Department of Energy, other federal agencies, and industry in support of:
Integrated Assessment Briefs. 1995. ORNL/M-4227. Oak Ridge National Laboratory, Oak Ridge, TN.