Mark Stephen Greeley, Jr.
Biological Monitoring Group
Environmental Sciences Division
Oak Ridge National Laboratory
Oak Ridge, TN 37831-6038
Phone: (865) 574-9387
Fax: (865) 576-8646
Reproductive and developmental toxicology, aquatic ecology, biomarkers of contaminant exposure and effects, methods of environmental assessment.
EducationPh.D., Biology, 1983, Univ. of Alabama at Birmingham
B.S., Biology - University of Alabama at Birmingham, 1978
Employment History1991-present: Research Staff Member, Environmental Sciences Division, Oak Ridge National Laboratory (ORNL)
1988-1991: Scientist II, Automated Sciences Group, Inc. (on assignment at ORNL)
1983-1988: Postdoctoral Research Associate, Whitney Marine Laboratory, University of Florida
1978-1983 Graduate Teaching and Research Fellow, University of Alabama at Birmingham
1974-1978: Undergraduate Laboratory Instructor, University of Alabama at Birmingham
- Over ten years experience managing ORNL Environmental Toxicology Laboratory
- Aquatic Biologist with over 30 years of Freshwater and Estuarine Research Experience
- Project Management, including Budget and Financial Analyses
- Environmental Effects Assessments and Monitoring
- Experience in numerous EPA and NIEHS Review Panels and Site Visits
- Participation in National Academy of Sciences Committee
Select Publications and Reports
- Southworth, G. R., S. C. Brooks, M.S. Greeley, Jr., R. H. Ketelle, and M.J. Peterson. In review. Sources of mercury to a contaminated stream – implications for time scale of effective remediation. Science of the Total Environment
- Greeley, M., L. Kszos, G. Morris, J. Smith and A. Stewart. In review. Role of a comprehensive toxicity assessment and monitoring program in the management and ecological recovery of a wastewater receiving stream. Environmental Management.
- Southworth, G., M. Greeley, M. Peterson., K. Lowe, and R. Ketelle (2010). Sources of mercury to East Fork Poplar Creek downstream from the Y-12 National Security Complex: Inventories and export rates. ORNL/TM-2009/231. Oak Ridge, TN. 69 pp.
- Alexander, S., et al. (2010). Assessing ecotoxicological effects of fly ash at the Kingston TN Site: A white paper addressing data gaps and requirements. Report on the Ecotoxicological Working Group at the TVA-Kingston Fly Ash Release Environmental Research Symposium, March 11-12, 2010. TVA/ORAU.
- National Research Council. (2005). Understanding Oil Spill Dispersants: Efficacy and Effects. The National Academies Press. Washington, D.C. 377 pp.
- Adams, S.M., M.S. Greeley, D.G. Fitzgerald, J.M. Law, E.J. Noga, and J.T. Zelikoff (2004). Effects of flooding from three sequential hurricanes on the health and condition of fish in Pamlico Sound, NC. Estuaries 26: 1365-1382.
- Hoyt, P. R., M. J. Doktycz, K. L. Beattie, and M. S. Greeley, Jr. (2003). DNA microarrays detect 4-nonylphenol-induced alterations in gene expression during zebrafish early development. Ecotoxicology 12: 469-474.
- Schrader, E. A., T. R. Henry, M. S. Greeley, Jr., and B. P. Bradley (2003). Proteomics in zebrafish exposed to endocrine disrupting chemicals. Ecotoxicology12: 485-488.
- Greeley, M.S., Jr. (2002). Reproductive Indicators of Environmental Stress
in Fish. Pp. 321-377 in S. M. Adams (ed), Biological Indicators of Stress.
American Fisheries Society, Bethesda, Maryland.
- McMaster, M.E., J. J. Jardine, G. Ankley, W. H. Benson, M. Greeley, T.
Gross, L. Guilette, D. MacLatchy, G. Van Der Kraak and K. R. Munkittrick.
(2001). An interlaboratory study on the use of steroid hormones in examining
endocrine disruption. Environ. Toxicol. Chem. 20: 2081 -2087.
- Adams, S.M. and M.S. Greeley. (2000). Ecotoxicological indicators of water
quality: Using multi-response indicators to assess the health of aquatic
ecosystems. J. of Water, Air, and Soil Pollution 123:103-115.
- Adams, S.M. and M.S. Greeley. (2000). Environmental challenges of water-quality
assessment using integrated bioindicators to evaluate aquatic ecosystem
health. Pages 103- 115 in S. Belkin (ed), Environmental challenges. Kluwer
Academic Pubs., London.
- Adams, S.M., M.S. Greeley, and M.G. Ryon. (2000). Evaluating effects
of stressors on fish health at multiple levels of biological organization:
Extrapolation from lower to higher levels. Human & Ecological Risk
Assessment 6: 15-27.
- Adams, S.M., M.S. Bevelhimer, M.S. Greeley. D.A. Levine, and S.J. Teh.
(1999). Ecological risk assessment in a large river-reservoir: 6. Bioindicators
of fish population health. Environ. Toxicol. Chem. 18:628-640.
- Greeley, M.S., Jr., T.L. Ashwood, L.A. Kszos, M.J. Peterson, T.L. Phipps,
C.D. Rash and G.R. Southworth. (1998). Postremediation Monitoring Program
Baseline Assessment Report, Lower East Fork Poplar Creek (Y/ER-319). Bechtel
Jacobs Company LLC, Oak Ridge, TN.
- Garcia, E. F., R. McPherson, T.H. Martin, R. A. Poth and M.S. Greeley,
Jr. (1997). Liver cell estrogen receptor binding in prespawning female
largemouth bass, Micropterus salmoides, environmentally exposed to polychlorinated
biphenyls (PCBs). Arch. Environm. Contam. Toxicol. 22: 309-315.
- Adams, S. M., K.D. Ham, M.S. Greeley, Jr., R.F. LeHew, D.E. Hinton, and
C.F. Saylor. (1996). Downstream gradients in bioindicator responses: Point
source contaminant effects on fish health. Can. J. Fish. Aquat. Sci. 53:
- Hsiao, S.-M., M. S. Greeley, and R. A. Wallace. (1994). Reproductive cycling
in female Fundulus heteroclitus. Biological Bulletin 186: 271-284.
- Adams, S.M., and M.S. Greeley, Jr. (1996) Establishing possible links and
relationships between aquatic ecosystem health and human health: An integrated
approach. Pages 91-102 in R.T. DiGiulio and E. Monosson (eds.), Interconnections
between Human and Ecosystem Health. Chapman and Hall, Publ.
- Greeley, M.S., Jr., S.M. Adams, W.D. Crumby, R. Epler, D.L. Harris, K.L.
Lee, M.K. McCracken, J.G. Mural, S.L. Niemela, R. McPherson, D.E. Hinton
and R. Stripp. (1994). Bioindicator Assessment of Fish Health and Reproductive
Success in Lake Hartwell and Twelve Mile Creek. In Biological Investigation
for the Remedial Investigation/Feasibility Study, Sangamo Weston, Inc./Twelve
Mile Creek/Lake Hartwell PCB Contamination Superfund Site. U.S. Army Corps
of Engineers, Savannah.
- Adams, S.M., G.F. Cada, M.S. Greeley, Jr., and L.R. Shugart. (1993). Evaluating
effects of environmental stress on fish communities using multi-response
indicators, pp. 170-177. In Environmental Analysis: The NEPA Experience
(S.G. Hildebrand and J.B. Cannon, eds.). Lewis Publ., Boca Raton, FL.
- Adams, S.M., W.D. Crumby, M.S. Greeley, Jr., and L.R. Shugart (1992). Responses
of fish populations and communities to pulp mill effluents: A holistic
assessment. Ecotoxicol. Environmental Safety 24: 347-360.
- Adams, S. M., W.D. Crumby, M.S. Greeley, Jr., M.G. Ryon, and E.M. Schilling
(1992). Relationship between physiological and fish population responses
in a contaminated stream.
Environ. Toxicol. Chem. 11: 1549-1557.
- Wallace, R.A., M.S. Jr. Greeley, and R. McPherson (1992). Analytical and
experimental studies on the relationship between Na+, K+, and water uptake
during volume increases associated with Fundulus oocyte maturation in vitro.
Journal of Comparative Physiology 162B: 241-248.
- Shugart, L. R., S. J. D’Surney, C. Getty-Hull, and M. S. Greeley, Jr. (1991).
Biological (Molecular and Cellular) Markers of Toxicity: Final Report to
the U. S. Army Biomedical Research and Development Laboratory (ORNL/M-1845).
Oak Ridge National Laboratory. Oak Ridge, TN.
- Adams, S. M., and M.S. Greeley, Jr. (1991). Assessment and evaluation of
the ecological health of fish populations exposed to PCBs in Hartwell Reservoir.
Tennessee Valley Authority Publ. TVA/WR/AB-91/14, Chattanooga, TN.
- Greeley, M.S., Jr., H. Hols, and R.A. Wallace (1991). Changes in size, hydration,
and low molecular weight osmotic effectors during meiotic maturation of Fundulus
oocytes in vivo. Comp. Biochem. Physiol. 100A: 639-647.
- McPherson, R., M. S. Greeley, Jr., and R. A. Wallace (1989). The influence
of yolk protein proteolysis on hydration in the oocytes of Fundulus heteroclitus.
Development, Growth and Differentiation 31: 475-483.
- Adams, S.M., K.L. Shepard, M.S. Greeley, Jr., B.D. Jimenez, M.G. Ryon, L.R.
Shugart, J.F. McCarthy, and D.E. Hinton (1989). The use of bioindicators
for assessing the effects of pollutant stress on fish. Mar. Environ. Res.
- Petrino, T. R., M. S. Greeley, Jr., K. Selman, Y-W. P. Lin, and R. A. Wallace
(1989). Steroidogenesis in Fundulus heteroclitus II. Production of 17α-hydroxy,
20ß-dihydroprogesterone, testosterone, and 17β-estradiol by various isolated
components of the ovarian follicle. Gen. Comp. Endocrinol. 76: 230-240.
- Lin, Y-W. P., M. S. Greeley, Jr., and R. A. Wallace (1989). Fundulus heteroclitus
gonadotropin(s) 2. Year-round husbandry of animals with active pituitaries
and responsive follicles. Fish Physiol. Biochem. 6: 139-148.
- Greeley, M. S., Jr., R. MacGregor III, and K. R. Marion (1988). Variation
in plasma estrogens of the gulf killifish (Fundulus grandis Baird and Girard).
J. Fish Biol. 33: 419-429.
- Greeley, M. S., Jr., D. R. Calder, and R. A. Wallace (1987). Oocyte growth and development during seasonal ovarian recrudescence in the striped mullet (Mugil cephalus): Relationship to fecundity and age at maturity. Fishery Bull. 85: 187-200.
- Principal Investigator, Fish reproduction and larval success research
projects related to the TVA Kingston (TN) Steam Plant Coal Ash Spill (2009-present)
- Editorial Board, Journal Ecotoxicology (2004 – present)
- Manager, Environmental Toxicology Laboratory, Oak Ridge National Laboratory,
- Project Manager, Biological Monitoring and Abatement Program, NNSA/DOE
Oak Ridge Y-12 National Security Complex (1996–2006)
- Member of National Academies Committee on Understanding Oil Spill Dispersants:
Effects and Efficacy (2004-2005)
- Project Manager, DOE Lower East Fork Poplar Creek Postremediation Monitoring
- ORNL Project Manager, DOD Ashumet and Johns Ponds Investigation, Massachusetts
Military Reservation (1993–1996)
- ORNL Project Manager, Biological Indicators Investigation, EPA/US Army Corps of Engineers, Sangamo Weston Inc./Hartwell Reservoir PCB Contamination Remedial Investigation (1992-1995)