Research Timeline
2015 - 2017
- Differential Hg-LMW thiols bioavailability to different microorganisms
- Point mutations of AA in HgcA confirms model predictions of Hg methylation
- Global distribution of hgcAB
- G. bemidjiensis methylates AND demethylates
- Seasonal and stormflow dynamics in Hg and MeHg transport
- Warming increases MeHg production in arctic soils
- Primers for hgcAB
- Periphyton biofilms important sources of MeHg
- Specific Hg-DOM molecules in DOM from HRMS
- C amendments affect Hg methylation and hgcA community structure
- Methanobactin and demethylation in methanotrophs
- New model of Hg methylation/demethylation kinetics by periphyton
2012 - 2014
- Hg-DOM log K increases with aging
- Active transport Hg into cells (PCA, ND132)
- Photochemical mechanisms w/ DOM – Hg oxidation and reduction, dark reduction with DOM
- Gene Discovery
- Predicted methylators based on gene discovery
- Computational chem. Inorganic Hg spp.
- First cut at Hg mass balance in EFPC
- Hg(0) can be fed into methylation pathway
- Natural Hg stable isotope fractionation to define sources and pathways
- Photooxidation Hg(0) carbonate
- Neutron spin echo & molecular dynamics mode of full length MerA (demethylation & supercomputers)
- How mer proteins control Hg transfer inter- & intra- protein
- DOM and photodemethylation mechanisms and influences
2009 - 2011
- mer mediated demethylation
- MerB – clearly defined mechanism
- MerA
- MerR
- History of Hg use at Y-12
- Hg spp. distribution in EFPC and log K determination Hg-DOM
- Kinetic controls Hg-DOM spp.
- DOM reduces and oxidizes Hg
- Microbial ecology of EFPC
- Genome sequences of methylators
- ND132 model methylator